Fulvether® 250mg/5ml Injection (Fulvestrant) – Hormone Therapy (Rx)

Quick answer: Fulvether 250mg (fulvestrant) is a hormone therapy injection for hormone receptor-positive advanced breast cancer, used alone or with a CDK4/6 tablet. A nurse injects it slowly into the buttock muscle from a prefilled syringe. MedHub supplies it on prescription and delivers it in cold-chain packaging across Pakistan.

For patients and families

What is Fulvether 250mg?

Fulvether 250mg is a ready-to-use prefilled syringe holding 250mg of fulvestrant in 5ml, marketed in Pakistan by LCI. Many breast cancers grow in response to the hormone oestrogen. Fulvestrant attaches to the oestrogen receptors on these cancer cells and breaks them down, so oestrogen can no longer push the tumour to grow. Doctors call it an oestrogen receptor downregulator.

What is it used for?

Fulvestrant treats breast cancer that is oestrogen receptor-positive and has spread or is locally advanced:

• In women after the menopause, either as their first hormone treatment or when the cancer grows despite earlier anti-oestrogen therapy
• Together with a CDK4/6 inhibitor such as palbociclib, in HER2-negative disease, in women who have already had hormone treatment

Women who have not reached the menopause may also receive it alongside palbociclib, with an extra medicine to switch off the ovaries.

How is it given?

A nurse or doctor gives Fulvether 250mg as a slow injection deep into the muscle of the buttock. A full treatment normally uses two syringes, one on each side, given at the same visit. Injections are more frequent during the first month and then settle into a monthly routine. Your doctor decides the exact schedule.

Common side effects

• Pain, bruising or swelling where the needle went in
• Hot flushes and sweating
• Joint and muscle aches
• Nausea and tiredness
• Raised liver enzymes on blood tests

Speak to your doctor quickly if you notice yellow skin, unusual bleeding or bruising, leg swelling or pain, or numbness and shooting pain down the leg after an injection.

Storage

Keep the syringes in the fridge at 2–8°C, inside the carton to block light. Bring them to the clinic in a cool bag. Read about how we keep medicines cold during delivery.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We pack the syringes in a cold-chain box and deliver them to your city or hospital.

Daughters and sons in the UAE, UK and Saudi Arabia often order Fulvether 250mg for a mother’s breast cancer care in Pakistan. When it is prescribed with a CDK4/6 inhibitor, see Oncolib 100mg (palbociclib). Other hormone options include Arimidex 1mg (anastrozole), and the full range is in oncology medicines.

For healthcare professionals

• Composition: fulvestrant 250 mg/5 ml (50 mg/ml) solution for injection in a prefilled syringe
• Drug class: selective oestrogen receptor degrader (SERD)
• Indications: oestrogen receptor-positive, locally advanced or metastatic breast cancer in postmenopausal women not previously treated with endocrine therapy, or with disease relapse or progression on or after antiestrogen therapy; in combination with palbociclib for HR-positive, HER2-negative locally advanced or metastatic breast cancer in women who have received prior endocrine therapy (with an LHRH agonist in pre- or perimenopausal women)
• Mechanism: competitively binds the oestrogen receptor, blocks its activity and accelerates receptor degradation
• Label dose: 500 mg given as two 5 ml intramuscular injections, one in each buttock, slowly over 1–2 minutes per injection, on days 1, 15 and 29, then once monthly
• Monitoring / key precautions: use with caution in patients with bleeding disorders, thrombocytopenia or on anticoagulants; take care near the sciatic nerve when injecting in the dorsogluteal site; not recommended in severe hepatic impairment; may interfere with immunoassay measurement of oestradiol; contraindicated in pregnancy and breastfeeding
• Storage: 2–8°C in the original package to protect from light
• Marketed in Pakistan by: LCI
• Pack: 1 prefilled syringe

Frequently asked questions

What is Fulvether 250mg used for?

It treats hormone receptor-positive breast cancer that is advanced or has spread. Doctors use it alone after the menopause or together with palbociclib.

What is the Fulvether 250mg price in Pakistan?

Fulvether 250mg costs Rs 22,000 to Rs 39,321 per prefilled syringe. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Can I get Fulvether 250mg in Lahore, Karachi or Peshawar?

Yes. MedHub delivers across Pakistan, including Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad, with every syringe kept cold on the way.

Do I need a prescription to buy Fulvether 250mg?

Yes. It is a prescription-only cancer medicine. Share a clear photo of the prescription on WhatsApp and our pharmacist checks it.

How is Fulvether 250mg injected?

A nurse injects it slowly into the buttock muscle. Each treatment visit usually needs two syringes, one in each buttock.

How many Fulvether 250mg syringes do I need each month?

Most patients receive two syringes at every visit. The first month has extra visits, so you need more syringes at the start. Your doctor confirms the number.

How should Fulvether 250mg be stored?

Store the syringes in a fridge at 2–8°C in their box, away from light.

Can I order Fulvether 250mg for my mother in Pakistan from abroad?

Yes. Families in the UAE, UK and Saudi Arabia order through MedHub. Send the prescription on WhatsApp and we arrange payment and cold-chain delivery to her home or hospital.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.