Herceptin® 440mg Injection (Trastuzumab) – Targeted Therapy (Rx)

Quick answer: Herceptin 440mg contains trastuzumab, a targeted therapy for HER2-positive breast cancer and HER2-positive stomach (gastric) cancer. This multi-dose vial is the intravenous form, so a nurse gives it as a drip into a vein. MedHub supplies it on prescription and delivers it in cold-chain packaging to every city in Pakistan.

For patients and families

What is Herceptin 440mg?

Herceptin is Roche’s brand of trastuzumab, a monoclonal antibody that blocks the HER2 protein on cancer cells. The 440mg vial contains a powder that the hospital pharmacy mixes and dilutes. Because the dose depends on your body weight, one vial can cover more than one dose, which is why it is called a multi-dose vial.

What is it used for?

Oncologists prescribe Herceptin 440mg for:

• HER2-positive early breast cancer: before or after surgery, often with chemotherapy
• HER2-positive advanced (metastatic) breast cancer
• HER2-positive advanced stomach cancer: together with chemotherapy

Herceptin helps only when a tumour test shows HER2-positive disease, so your doctor confirms this before treatment starts.

How is it given?

A nurse gives Herceptin as a drip into a vein at a hospital or day-care unit. The first infusion takes about 90 minutes. If you tolerate it well, later infusions usually take about 30 minutes. Most patients receive it once every three weeks, and some receive it weekly. Your doctor works out the dose from your weight and decides how long you need it.

Your team checks your heart with an echo scan before and during treatment, because trastuzumab can weaken the heart muscle in some people.

Common side effects

• Fever, chills or flu-like symptoms, mostly during the first infusion
• Tiredness and headache
• Nausea or loose stools
• Aching joints or muscles

Call your doctor straight away if you feel short of breath, notice swollen ankles or feel your heart racing. Women should avoid pregnancy during treatment and for seven months after the last dose.

Storage

Keep the vial in its box in the fridge at 2–8°C and never freeze it. If you collect it before your appointment, take it to the hospital in a cool bag with ice packs. Read more about how we keep medicines cold during delivery.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We pack the vial in a cold-chain box and deliver it to your city or hospital.

Families abroad often arrange Herceptin for parents in Pakistan through us. If your oncologist prefers the injection under the skin, see Herceptin 600mg (subcutaneous). You can also look at Kadcyla 160mg (trastuzumab emtansine) or browse all oncology medicines.

For healthcare professionals

• Composition: trastuzumab 440 mg, lyophilised powder for concentrate for solution for infusion (multi-dose vial)
• Drug class: humanized IgG1 monoclonal antibody (HER2 inhibitor)
• Indications: HER2-positive early breast cancer; HER2-positive metastatic breast cancer; HER2-positive metastatic adenocarcinoma of the stomach or gastro-oesophageal junction, with chemotherapy
• Mechanism: binds the extracellular domain of HER2, inhibits HER2-driven tumour cell proliferation and triggers antibody-dependent cellular cytotoxicity
• Label dose (3-weekly): 8 mg/kg loading dose, then 6 mg/kg every 3 weeks
• Label dose (weekly, breast cancer): 4 mg/kg loading dose, then 2 mg/kg every week
• Infusion: loading dose over 90 minutes; later doses over 30 minutes if well tolerated
• Monitoring: assess LVEF at baseline and during treatment
• Storage: 2–8°C; do not freeze
• Manufacturer: F. Hoffmann-La Roche Ltd, Switzerland
• Marketed in Pakistan by: Roche Pakistan Ltd
• Pack: 1 multi-dose vial

Frequently asked questions

What is Herceptin 440mg used for?

Herceptin 440mg treats HER2-positive breast cancer, in early and advanced stages, and HER2-positive advanced stomach cancer. Your oncologist prescribes it only after a tumour test confirms HER2-positive disease.

What is the Herceptin 440mg price in Pakistan?

Herceptin 440mg costs Rs 139,100 per vial. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

What is the difference between Herceptin 440mg and Herceptin 600mg?

Herceptin 440mg goes into a vein as a drip, and the dose depends on body weight. Herceptin 600mg goes under the skin in a few minutes at a fixed dose. Your oncologist decides which form suits you.

Can I get Herceptin 440mg in Lahore, Karachi or Peshawar?

Yes. MedHub delivers Herceptin 440mg across Pakistan, including Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad. We pack every vial in a cold-chain box to keep it at 2–8°C on the way.

Do I need a prescription to buy Herceptin 440mg?

Yes. Herceptin is a prescription-only medicine. Send a clear photo of your oncologist’s prescription on WhatsApp, and our pharmacist checks it before confirming your order.

How is Herceptin 440mg given?

A nurse gives Herceptin 440mg as a drip into a vein. The first infusion takes about 90 minutes, and later infusions usually take about 30 minutes, most often once every three weeks.

How should I store Herceptin 440mg?

Keep Herceptin in its original box in the fridge at 2–8°C and never freeze it. Carry it to the hospital in a cool bag with ice packs, and keep the vial from touching the ice.

Can I order Herceptin 440mg for my parents in Pakistan from abroad?

Yes. Many families in the UAE, UK and Saudi Arabia order Herceptin through MedHub for parents in Pakistan. Share the prescription on WhatsApp, and our team guides you through payment and delivery to their home or hospital.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.