Nautant® 80mg Capsules (Aprepitant) – Anti-Nausea Medicine (Rx)

Quick answer: Nautant 80mg (aprepitant) is an anti-sickness capsule that helps prevent the nausea and vomiting chemotherapy can cause, especially in the days after treatment. You take it by mouth alongside other anti-sickness medicines. MedHub supplies it on prescription and delivers it across Pakistan.

For patients and families

What is Nautant 80mg?

Nautant 80mg is a pack of two aprepitant capsules made in Pakistan by Pharmasol. Aprepitant belongs to a group called NK1 receptor blockers. It stops a natural chemical, substance P, from reaching the part of the brain that triggers vomiting. That action matters most in the second and third days after chemotherapy, when delayed sickness often sets in.

What is it used for?

Oncologists prescribe aprepitant to prevent sickness in adults and teenagers from 12 years old who receive:

• Highly emetogenic chemotherapy: treatment that very often causes vomiting, such as cisplatin-based regimens.
• Moderately emetogenic chemotherapy: treatment that causes sickness in a sizeable share of patients.

It works best as part of a combination, usually with a steroid and another anti-sickness medicine. It prevents sickness rather than treating vomiting that has already started.

How is it taken?

You swallow the capsules whole with water, with or without food. The 80mg capsules usually follow a first, larger capsule given on the day of chemotherapy. Your doctor or pharmacist explains exactly which day to take each capsule, and your doctor decides the dose.

Common side effects

• Hiccups
• Tiredness or weakness
• Constipation or indigestion
• Headache and reduced appetite

Get medical help straight away if you notice swelling of the face or throat, wheezing, a widespread rash, or sickness so severe that you cannot keep fluids down.

Aprepitant can make hormonal birth control less reliable for about a month, so ask your doctor about a backup method. Tell your doctor if you take warfarin, since you may need extra blood tests.

Storage

Keep the capsules in their blister below 30°C and away from moisture. Store them where children cannot reach them.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We deliver the pack to your home or hospital before your next cycle.

Families in the UAE, UK and Saudi Arabia often order Nautant 80mg together with the starter pack, Nautant 125mg + 80mg, so a parent has the full course ready before chemotherapy. If the regimen includes Cispatin 50mg (cisplatin), we can send both together. You can also browse our oncology medicines.

For healthcare professionals

• Composition: aprepitant 80 mg per hard capsule
• Drug class: selective neurokinin-1 (NK1) receptor antagonist, antiemetic
• Indications: prevention of acute and delayed nausea and vomiting associated with highly emetogenic cisplatin-based cancer chemotherapy and moderately emetogenic cancer chemotherapy in adults and adolescents from 12 years, as part of combination therapy
• Mechanism: blocks substance P binding at central NK1 receptors; augments the antiemetic effect of 5-HT3 antagonists and corticosteroids
• Label dose: 3-day regimen of 125 mg orally 1 hour before chemotherapy on day 1, then 80 mg once daily in the morning on days 2 and 3, with a corticosteroid and a 5-HT3 antagonist
• Monitoring / key precautions: moderate CYP3A4 inhibitor and inducer; contraindicated with pimozide, terfenadine, astemizole and cisapride; reduce oral dexamethasone and methylprednisolone doses; monitor INR in patients on warfarin; hormonal contraception may fail during and for 28 days after treatment; caution in severe hepatic impairment
• Storage: below 30°C; protect from moisture
• Manufactured and marketed in Pakistan by: Pharmasol (Pvt) Ltd
• Pack: 2 capsules

Frequently asked questions

What is Nautant 80mg used for?

It helps prevent nausea and vomiting caused by chemotherapy, particularly delayed sickness on the days after treatment. Doctors combine it with a steroid and another anti-sickness medicine.

What is the Nautant 80mg price in Pakistan?

Nautant 80mg costs Rs 2,000 per pack of 2 capsules. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Can I get Nautant 80mg in Lahore, Karachi or Peshawar?

Yes. We deliver across Pakistan, including Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad.

Does Nautant 80mg need a prescription?

Yes. Aprepitant is prescribed by your cancer doctor as part of your chemotherapy plan. Send a photo of the prescription on WhatsApp, and our pharmacist checks it first.

How do I take Nautant 80mg?

Swallow each capsule whole with water, with or without food, on the days your doctor tells you. Most plans use these capsules after a larger first dose on chemotherapy day.

Why does the Nautant 80mg pack contain only two capsules?

The standard course uses one 80mg capsule on each of the two days after chemotherapy. Two capsules cover those days for one cycle, so you need a fresh pack for every cycle.

Can Nautant 80mg stop vomiting that has already started?

No. Aprepitant works to prevent sickness, so you take it on schedule even if you feel well. If vomiting breaks through, call your doctor, who may add another rescue medicine.

Can I order Nautant 80mg from abroad for my parents?

Yes. Children living in the UAE, UK and Saudi Arabia often order for parents having chemotherapy in Pakistan. Share the prescription on WhatsApp, and we arrange payment and delivery.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.