Oncolib® 100mg Tablets (Palbociclib) – Targeted Therapy (Rx)

Quick answer: Oncolib 100mg (palbociclib) is an oral targeted tablet for hormone receptor-positive, HER2-negative breast cancer that has spread or come back. Doctors prescribe it together with hormone therapy. MedHub supplies it on prescription and delivers across Pakistan.

For patients and families

What is Oncolib 100mg?

Oncolib 100mg is a palbociclib tablet marketed in Pakistan by Oncogen Pharma. Palbociclib belongs to a group called CDK4/6 inhibitors. These proteins act like an accelerator inside breast cancer cells. Palbociclib holds the accelerator back, so the cells divide more slowly and the cancer is easier to control. It always works alongside a hormone medicine.

What is it used for?

Breast cancer specialists prescribe palbociclib for women (and sometimes men) with advanced or metastatic breast cancer that is hormone receptor-positive and HER2-negative. The usual pairings are:

• With an aromatase inhibitor: as the first hormone-based treatment for advanced disease.
• With fulvestrant: after earlier hormone therapy has stopped working.

Common partners include Arimidex 1mg (anastrozole) and Fulvether 250mg/5ml (fulvestrant). For other breast cancer treatments, see our oncology medicines.

How is it taken?

You swallow the tablet whole with water, at the same time each day, in cycles that include a rest break. Your doctor or pharmacist explains how to take it. Your oncologist decides the dose and often lowers it when blood counts drop, which is why a 100mg strength exists next to the standard one. Do not take extra tablets to make up for a missed one.

Common side effects

• Low white blood cell counts, which raise the risk of infection
• Tiredness and weakness
• Nausea, mouth sores and diarrhoea
• Hair thinning and rash
• Low red cells (anaemia) and low platelets

Call your care team straight away if you have a fever of 38°C or above, chills, a new cough with breathlessness, or unusual bleeding.

Storage

Store the tablets in the original pack below 30°C, away from moisture and out of children’s reach. A fridge is not needed. Avoid grapefruit and grapefruit juice while you are on treatment.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We deliver the pack to your home or hospital.

Daughters and sons in the UAE, UK and Saudi Arabia often arrange breast cancer treatment for a mother in Pakistan. Send us the prescription and your delivery address, and we organize repeat packs on the schedule your oncologist sets.

For healthcare professionals

• Composition: palbociclib 100 mg per film-coated tablet
• Drug class: cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor
• Indications: HR-positive, HER2-negative locally advanced or metastatic breast cancer, in combination with an aromatase inhibitor or with fulvestrant after prior endocrine therapy; in pre- or perimenopausal women, combine endocrine therapy with an LHRH agonist
• Mechanism: inhibits CDK4/6, which prevents retinoblastoma protein phosphorylation and blocks progression from G1 to S phase
• Label dose: 125 mg once daily for 21 consecutive days, then 7 days off, in a 28-day cycle; reduce to 100 mg and then 75 mg for toxicity; tablets may be taken with or without food
• Monitoring / key precautions: full blood count before treatment, at the start of each cycle and on day 15 of the first two cycles; monitor for neutropenia, infection and interstitial lung disease or pneumonitis; avoid strong CYP3A inhibitors and inducers; effective contraception during and after treatment; avoid in pregnancy
• Storage: below 30°C, protect from moisture
• Marketed in Pakistan by: Oncogen Pharma
• Pack: 7 tablets

Frequently asked questions

What is Oncolib 100mg used for?

Oncolib 100mg treats hormone receptor-positive, HER2-negative advanced breast cancer, together with hormone therapy.

What is the Oncolib 100mg price in Pakistan?

Oncolib 100mg costs Rs 10,000 to Rs 24,000 per pack of 7 tablets. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Can I get Oncolib 100mg in Lahore, Karachi or Peshawar?

Yes. MedHub delivers to Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad, and to other cities on request.

Do I need a prescription for Oncolib 100mg?

Yes. It is a prescription-only cancer medicine. Send a clear photo of your oncologist’s prescription on WhatsApp, and our pharmacist checks it first.

How is Oncolib 100mg taken?

Swallow the tablet whole with water at about the same time every day, as your oncologist directs. Do not crush or chew it.

How should Oncolib 100mg be stored?

Keep it below 30°C in the original pack, away from damp and out of children’s reach. It does not need refrigeration.

Why do I have a 7-tablet pack of Oncolib 100mg?

A pack of seven covers one week. Because a standard cycle runs three weeks on and one week off, you need several packs per cycle, and your dose may differ if your doctor has reduced it.

Can I order Oncolib 100mg for my mother in Pakistan from abroad?

Yes. Many families in the UAE, UK and Saudi Arabia order through MedHub. Share the prescription on WhatsApp, and we arrange payment and delivery to her home.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.