Sunetic® 12.5mg Capsules (Sunitinib) – Targeted Therapy (Rx)

Quick answer: Sunetic 12.5mg (sunitinib) is the smallest capsule strength of this targeted cancer medicine. Oncologists use it to adjust doses in small steps for kidney cancer, GIST and pancreatic neuroendocrine tumours, often alongside a larger capsule. MedHub supplies it on prescription and delivers across Pakistan.

For patients and families

What is Sunetic 12.5mg?

Sunetic 12.5mg is a low-strength sunitinib capsule. Pharmasol manufactures it in Pakistan and markets it here. Sunitinib slows cancer growth by cutting off the chemical messages that tumours rely on, including the ones that build a blood supply. Because the right dose varies from person to person, this small capsule lets your oncologist set a dose that suits your body.

What is it used for?

Sunitinib is approved for the following cancers, and the 12.5mg strength helps fine-tune treatment in each:

• Pancreatic neuroendocrine tumours: a rare tumour of the hormone-producing cells of the pancreas, when it is growing and cannot be removed.
• Gastrointestinal stromal tumour (GIST): after imatinib has failed or caused intolerable side effects.
• Renal cell carcinoma: kidney cancer that is advanced or has spread.

How is it taken?

Sunetic is taken by mouth once daily. Swallow the capsules whole with water, either with a meal or without one. If you miss a dose, do not double up the next day. Your doctor decides the dose, which may mean taking a 12.5mg capsule together with a 25mg or 50mg capsule, and your pharmacist explains the combination clearly.

Common side effects

• Diarrhoea and an upset stomach
• Tender, blistering skin on the palms or soles
• Feeling very tired
• Raised blood pressure
• Sore mouth, altered taste and loss of appetite

Speak to your care team at once if you notice yellow eyes, unusual bleeding or bruising, severe headache with confusion, a racing heart, or jaw pain after dental work.

Storage

Store the capsules below 30°C in the pack they came in, protected from humidity. Keep each strength in its own box so you can tell them apart, and keep them out of children’s reach.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We deliver to your home or hospital, anywhere in Pakistan.

Overseas Pakistanis in the UAE, UK and Saudi Arabia often order Sunetic 12.5mg for parents at home together with the larger strength in one delivery. Pair it with Sunetic 25mg or Sunetic 50mg as your oncologist directs. For advanced kidney cancer, our range also includes Sonib 200mg (sorafenib), and you can view all oncology products.

For healthcare professionals

• Composition: sunitinib (as malate) 12.5 mg per hard capsule
• Drug class: small-molecule receptor tyrosine kinase inhibitor
• Indications: unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumours with progression; advanced or metastatic renal cell carcinoma; GIST after failure of imatinib because of resistance or intolerance
• Mechanism: inhibits VEGFR-1, -2 and -3, PDGFR-α and -β, stem cell factor receptor (KIT), FLT3, CSF-1R and RET
• Label dose: pNET: 37.5 mg orally once daily, continuous dosing; RCC and GIST: 50 mg once daily, 4 weeks on followed by 2 weeks off. Increase or reduce in 12.5 mg steps according to individual safety and tolerability
• Monitoring / key precautions: hepatotoxicity (boxed warning): monitor liver tests at baseline, during each cycle and as clinically indicated; regular blood pressure, full blood count, thyroid function and blood glucose; urinalysis for proteinuria; ECG and LVEF assessment in patients at cardiac risk; monitor for haemorrhage, thrombotic microangiopathy and osteonecrosis of the jaw; hold before elective surgery; adjust dose with strong CYP3A4 modulators; contraception required
• Storage: below 30°C; protect from moisture
• Manufactured and marketed in Pakistan by: Pharmasol (Pvt) Ltd
• Pack: 30 capsules

Frequently asked questions

Why is Sunetic 12.5mg prescribed?

Sunetic 12.5mg lets oncologists adjust sunitinib doses in small steps for kidney cancer, GIST and pancreatic neuroendocrine tumours. It is often taken alongside a 25mg or 50mg capsule.

What is the Sunetic 12.5mg price in Pakistan?

Sunetic 12.5mg costs Rs 18,000 to Rs 25,000 per pack of 30 capsules. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Is Sunetic 12.5mg delivered to Lahore, Karachi or Peshawar?

Yes. MedHub sends orders to Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad, and to other cities and towns in Pakistan.

Will I need a prescription to buy Sunetic 12.5mg?

Yes. You need a valid oncologist’s prescription. Share a photo of it on WhatsApp so our pharmacist can check the strength and quantity before dispatch.

How do I take Sunetic 12.5mg?

Take it once a day by mouth, with or without food, as part of the total dose your doctor sets. Swallow the capsules whole and keep to the same time daily.

Why take Sunetic 12.5mg with another capsule instead of one larger one?

Sunitinib comes in fixed strengths, so some doses, such as 37.5mg, need two capsules. Combining strengths gives the exact amount without splitting or opening capsules.

Can my dose of Sunetic 12.5mg go up later?

It can. For pancreatic neuroendocrine tumours, doctors may raise the daily dose in 12.5mg steps if you handle treatment well. They may also lower it if side effects become hard to manage.

How do I order Sunetic 12.5mg for my parents while living abroad?

Send the prescription on WhatsApp from the UAE, UK, Saudi Arabia or elsewhere. We confirm stock, arrange payment and deliver to your parents in Pakistan.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.