Rubisol® 10mg/5ml Injection (Epirubicin) – Chemotherapy (Rx)

Quick answer: Rubisol 10mg (epirubicin) is an anthracycline chemotherapy injection used mainly for breast cancer, and also for stomach, lung, ovarian and bladder cancers, lymphomas and sarcomas. A trained nurse gives it into a vein, or into the bladder for some bladder tumours. MedHub supplies it on prescription with cold-chain delivery across Pakistan.

For patients and families

What is Rubisol 10mg?

Rubisol 10mg is a small vial holding 10mg of epirubicin in 5ml of ready-made solution, produced in Pakistan by Pharmasol. Epirubicin is a red-coloured chemotherapy medicine from the anthracycline family. It slips between the strands of DNA inside cancer cells and stops them copying themselves, so the cells die.

What is it used for?

Oncologists use epirubicin, usually in combination with other medicines, for:

• Breast cancer: after surgery when lymph nodes are involved, and for advanced disease
• Stomach cancer that is advanced
• Small cell lung cancer
• Ovarian cancer
• Lymphomas and soft tissue sarcomas
• Early bladder cancer: given directly into the bladder to lower the chance of the tumour coming back

The 10mg vial is mainly used to top up a dose. For larger doses, the pharmacy usually starts with Rubisol 50mg/25ml.

How is it given?

The hospital team gives epirubicin as an injection or short drip into a vein, usually on day 1 of a three-week cycle. The nurse watches the cannula site closely, because this medicine damages the skin if it leaks outside the vein. Your doctor decides the dose from your height, weight, blood counts and liver tests, and checks your heart before and during treatment.

Common side effects

• Red or pink urine for a day or two, which is harmless
• Hair loss, usually starting two to three weeks after the first dose
• Nausea, vomiting and a sore mouth
• Low blood counts and a higher risk of infection
• Tiredness and missed periods

Call your care team straight away if you develop a temperature of 38°C or above, pain or swelling where the drip went in, a racing heartbeat, breathlessness or swollen ankles.

Storage

Keep the vial in a fridge at 2–8°C, inside its box to shield it from light, and do not freeze it. Hospitals normally store and prepare it for you. Read about how we keep medicines cold during delivery.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We deliver the vials in a cold-chain box to your city or hospital.

Families in the UAE, UK and Saudi Arabia often arrange Rubisol 10mg for a parent’s chemotherapy in Pakistan through MedHub. For other anthracycline regimens, look at Naprodox 50mg (doxorubicin), or see all our oncology medicines.

For healthcare professionals

• Composition: epirubicin hydrochloride 2 mg/ml; 10 mg in 5 ml solution for injection
• Drug class: anthracycline cytotoxic antibiotic
• Indications: breast carcinoma (including adjuvant therapy in axillary node-positive disease); advanced gastric cancer; small cell lung cancer; ovarian cancer; malignant lymphomas; soft tissue sarcomas; intravesical treatment of superficial bladder cancer (papillary transitional cell carcinoma, carcinoma in situ) and prophylaxis of recurrence after transurethral resection
• Mechanism: intercalates between DNA base pairs and inhibits topoisomerase II, blocking DNA and RNA synthesis; also generates free radicals
• Label dose: single agent 60–90 mg/m² IV every 21 days; adjuvant breast cancer 100–120 mg/m² per cycle in combination regimens; intravesical 50 mg in 50 ml saline weekly for 8 weeks; reduce dose in hepatic impairment and after prior myelosuppressive therapy
• Monitoring / key precautions: baseline and periodic LVEF; cumulative dose generally not above 900 mg/m² because of cardiotoxicity, lower after mediastinal radiotherapy or other anthracyclines; full blood count before each cycle; bilirubin and AST; serum creatinine; strong vesicant, avoid extravasation; risk of secondary AML/MDS; contraindicated in pregnancy and breastfeeding
• Storage: 2–8°C, protect from light
• Manufactured and marketed in Pakistan by: Pharmasol (Pvt) Ltd
• Pack: 1 vial

Frequently asked questions

What is Rubisol 10mg used for?

Rubisol 10mg is used mainly for breast cancer. Specialists also give epirubicin for stomach, small cell lung and ovarian cancers, lymphomas, sarcomas and early bladder cancer.

What is the Rubisol 10mg price in Pakistan?

Rubisol 10mg costs Rs 1,500 per vial. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Is Rubisol 10mg available in Lahore, Karachi or Peshawar?

Yes. We deliver it in cold-chain packaging to Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan, Faisalabad and other cities.

Do I need a prescription for Rubisol 10mg?

Yes. Epirubicin is a prescription-only chemotherapy. Send your oncologist’s prescription on WhatsApp, and our pharmacist confirms it before dispatch.

How is Rubisol 10mg given?

A nurse gives it into a vein through a drip or slow injection at a hospital or chemotherapy unit. For some bladder tumours, the urologist puts it directly into the bladder through a thin tube.

Why does urine turn red after Rubisol 10mg?

Epirubicin is a red liquid, and some of it leaves the body in urine for one to two days. This colour change is expected and harmless, but report blood clots or pain when passing urine.

Why would a hospital order Rubisol 10mg vials instead of 50mg?

Doses are worked out from body size, so they rarely match one vial. Pharmacists combine 50mg vials with 10mg vials to reach the exact amount and reduce waste.

Can relatives abroad order Rubisol 10mg for parents in Pakistan?

Yes. Families in the UAE, UK and Saudi Arabia order through MedHub regularly. Send the prescription on WhatsApp and we deliver the chilled vials to the home or hospital.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.