Relitrexed® 100mg Injection (Pemetrexed) – Chemotherapy (Rx)

Quick answer: Relitrexed 100mg (pemetrexed) is the smaller vial of an antifolate chemotherapy for mesothelioma and non-squamous non-small cell lung cancer. Hospital staff give it through a vein, often with larger vials to reach the exact dose. MedHub supplies it on prescription and delivers it nationwide in Pakistan.

For patients and families

What is Relitrexed 100mg?

Relitrexed 100mg holds 100 milligrams of pemetrexed as a dry powder, produced by Reliance Life Sciences in India. Pharmacists dissolve and dilute it shortly before use. Pemetrexed starves cancer cells of the building blocks they need to make new DNA, which slows or stops tumour growth. Because chemotherapy doses depend on body size, this small vial lets the pharmacy fine-tune the total amount.

What is it used for?

Oncologists use pemetrexed for two cancers:

• Mesothelioma of the pleura, the thin lining that covers the lungs, given with cisplatin when an operation is not an option.
• Non-squamous non-small cell lung cancer, either first with cisplatin, as ongoing maintenance after platinum chemotherapy, or alone when an earlier treatment has stopped working.

Your doctor checks the type of lung cancer under the microscope first, since pemetrexed does not suit the squamous type.

How is it given?

You receive it as a short infusion into a vein, lasting roughly ten minutes, in a chemotherapy unit. Treatment usually repeats every 21 days. Your doctor decides the dose and checks your kidneys and blood counts before every cycle.

Before the first cycle, you begin folic acid tablets and receive a vitamin B12 injection. Your team also gives steroid tablets for a few days around each dose to reduce rashes.

Common side effects

• Fall in white cells, red cells or platelets
• Itchy or red skin rash
• Sore mouth and feeling sick
• Fatigue, poor appetite and constipation or diarrhoea

Contact the hospital at once if you develop a fever, chills, sudden breathlessness, severe diarrhoea, blistering skin or very little urine.

Storage

Store unopened vials between 15°C and 30°C in the carton. Never freeze them, and keep them out of direct sun. Hospitals normally handle storage and preparation for you.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We deliver the vials to the treating hospital or your home address.

Families in the UAE, UK and Saudi Arabia often order Relitrexed 100mg with the larger Relitrexed 500mg vial, so the full dose arrives in one delivery. Patients on combination treatment may also need Cispatin 50mg. See all our oncology medicines.

For healthcare professionals

• Composition: pemetrexed (as disodium) 100 mg per vial, lyophilized powder for concentrate for solution for infusion
• Drug class: folate analogue metabolic inhibitor (antifolate)
• Indications: malignant pleural mesothelioma, unresectable, in chemotherapy-naive patients with cisplatin; locally advanced or metastatic NSCLC other than predominantly squamous histology as first-line therapy with cisplatin, as maintenance after platinum-based chemotherapy without progression, and as second-line monotherapy
• Mechanism: inhibits thymidylate synthase, dihydrofolate reductase and GARFT, blocking folate-dependent nucleotide synthesis
• Label dose: 500 mg/m² by 10-minute IV infusion on day 1 of each 21-day cycle, alone or followed by cisplatin 75 mg/m²
• Monitoring / key precautions: mandatory folic acid (350–1000 micrograms daily, from 7 days before until 21 days after treatment) and vitamin B12 (1000 micrograms IM every 9 weeks) supplementation; dexamethasone prophylaxis for skin reactions; full blood count and renal function before each cycle; avoid if creatinine clearance is below 45 ml/min; caution with NSAIDs and nephrotoxic drugs; drain clinically significant effusions before dosing; contraception during treatment
• Storage: 15–30°C; do not freeze
• Manufacturer: Reliance Life Sciences, India
• Pack: 1 vial

Frequently asked questions

Which cancers does Relitrexed 100mg treat?

It treats pleural mesothelioma and non-squamous non-small cell lung cancer. Doctors give it with cisplatin or on its own, depending on the stage.

What is the Relitrexed 100mg price in Pakistan?

Relitrexed 100mg costs Rs 12,000 to Rs 14,950 per vial. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Do you deliver Relitrexed 100mg to Lahore, Karachi or Peshawar?

Yes. We deliver across the country, including Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad.

Is a prescription required for Relitrexed 100mg?

Yes. Only an oncologist can prescribe pemetrexed. WhatsApp us a photo of the prescription, and our pharmacist reviews it before your order goes out.

How do hospitals give Relitrexed 100mg?

A chemotherapy nurse runs it into a vein over about ten minutes, generally every three weeks. Vitamin and steroid tablets go alongside it.

Why would my prescription include Relitrexed 100mg as well as 500mg vials?

Your dose depends on your body surface area, so it rarely matches one vial exactly. The pharmacy adds 100mg vials to a 500mg vial to reach the precise amount and reduce waste.

How many Relitrexed 100mg vials will I need?

That depends on your calculated dose and whether you also use the larger vial. Send us your prescription, and our pharmacist works out the exact number of vials with you.

Can family members overseas order Relitrexed 100mg for a parent?

Yes. Relatives in the UAE, UK and Saudi Arabia often pay from abroad, and we deliver to the parent’s hospital in Pakistan. Send the prescription on WhatsApp to start.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.