Glynib® 100mg Capsules (Imatinib) – Targeted Therapy (Rx)

Quick answer: Glynib 100mg (imatinib) is a capsule made in Pakistan by Pharmasol for chronic myeloid leukaemia (CML) and gastrointestinal stromal tumours (GIST). Patients take it by mouth at home, and the small strength lets doctors fine-tune the daily dose. MedHub supplies it on prescription with delivery across Pakistan.

For patients and families

What is Glynib 100mg?

Glynib 100mg is a hard capsule containing 100mg of imatinib, produced and marketed locally by Pharmasol (Pvt) Ltd. Imatinib was one of the first targeted cancer medicines. It blocks an abnormal enzyme, BCR-ABL in CML and KIT in GIST, that tells cancer cells to keep growing. Healthy cells rely far less on these signals, which is why imatinib works differently from traditional chemotherapy.

What is it used for?

Specialists prescribe imatinib capsules for:

• CML: Philadelphia chromosome-positive chronic myeloid leukaemia in adults and children.
• GIST: KIT-positive stomach or bowel tumours that have spread or cannot be removed, and as follow-on treatment after surgery.
• Ph-positive ALL: a form of acute leukaemia, usually combined with chemotherapy.
• Less common disorders: hypereosinophilic syndrome, systemic mastocytosis, certain myeloproliferative diseases and dermatofibrosarcoma protuberans.

Doctors often choose the 100mg capsule for children, for patients whose dose has been reduced, or to build a dose such as 300mg or 600mg. Adults on a standard dose may use Glynib 400mg tablets instead.

How is it taken?

Swallow the capsules whole with food and plenty of water. Your doctor decides how many capsules you need each day, and your pharmacist explains how to take them. Keep taking them every day unless your doctor tells you to stop, even when you feel completely well. Grapefruit and St John’s wort can change how imatinib works, so avoid them and mention every medicine you use.

Common side effects

• Feeling sick or loose stools, especially if a dose is taken on an empty stomach
• Swelling of the eyelids, face or legs
• Cramps in the hands, calves or feet
• Itchy rash or dry skin
• Lower white cell, red cell or platelet counts

Tell your doctor at once if you notice sudden weight gain, breathlessness, dark urine or yellowing eyes, a high temperature, or bruising and bleeding.

Storage

Store the capsules below 30°C in the original packaging, which protects them from humidity. Do not move them into a pill box for long periods during the monsoon months, and keep them where children cannot reach them.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We pack the capsules carefully and deliver them to your door.

Because imatinib is taken for many years, sons and daughters in the UAE, UK and Saudi Arabia often set up Glynib 100mg refills for their parents through us. Other options in our range include Imatigliv 100mg (imatinib) and Nitonib 200mg (nilotinib). See every product in our oncology range.

For healthcare professionals

• Composition: imatinib (as mesylate) 100 mg per hard capsule
• Drug class: protein tyrosine kinase inhibitor (BCR-ABL, KIT, PDGFR)
• Indications: newly diagnosed and previously treated Ph+ CML (chronic, accelerated and blast phase) in adults and paediatric patients; Ph+ ALL; MDS/MPD associated with PDGFR rearrangements; aggressive systemic mastocytosis; HES/CEL; DFSP; Kit (CD117)-positive unresectable or metastatic GIST; adjuvant treatment following GIST resection
• Mechanism: binds the ATP pocket of the BCR-ABL kinase and inhibits KIT and PDGFR signalling, leading to reduced proliferation and apoptosis of dependent tumour cells
• Label dose: adults: CML chronic phase 400 mg daily, advanced phases 600 mg daily, GIST 400 mg daily; paediatric CML 340 mg/m² daily (maximum 600 mg); HES/CEL with FIP1L1-PDGFRα 100 mg daily; doses of 800 mg given as 400 mg twice daily; take with food and a large glass of water
• Monitoring / key precautions: blood counts weekly in month 1, every 2 weeks in month 2, then as indicated; liver tests monthly; monitor weight and for fluid retention; hepatitis B screening; caution in cardiac or renal impairment; CYP3A4 interactions; growth monitoring in children; avoid in pregnancy
• Storage: below 30°C, protect from moisture
• Manufactured and marketed in Pakistan by: Pharmasol (Pvt) Ltd
• Pack: 120 capsules

Frequently asked questions

What conditions does Glynib 100mg treat?

Glynib 100mg treats chronic myeloid leukaemia (CML) and GIST, along with Philadelphia-positive ALL and some rare blood and skin conditions that respond to imatinib.

What is the Glynib 100mg price in Pakistan?

Glynib 100mg costs Rs 20,000 to Rs 41,000 per pack of 120 capsules. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Is Glynib 100mg available in Lahore, Karachi or Peshawar?

Yes. MedHub sends Glynib to all major cities, including Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad, as well as smaller towns.

Is a prescription required for Glynib 100mg?

Yes. We only dispense imatinib against a valid prescription from a cancer specialist. Send a photo of it on WhatsApp and our pharmacist reviews it.

Who usually takes Glynib 100mg capsules?

Children with CML, adults whose dose has been lowered because of side effects, and patients on doses such as 300mg or 600mg commonly use the 100mg capsule. Your doctor works out the right number of capsules.

Is Glynib 100mg made in Pakistan?

Yes. Pharmasol (Pvt) Ltd makes and markets Glynib in Pakistan. It contains imatinib, the same active ingredient found in every imatinib brand.

How do I store Glynib 100mg at home?

Keep the capsules below 30°C in their original pack, away from damp places such as the kitchen sink or bathroom.

Can family abroad order Glynib 100mg for parents in Pakistan?

Yes. Families in the UAE, UK and Saudi Arabia regularly order through MedHub. Share the prescription on WhatsApp, pay online, and we deliver to your parents’ address.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.