Sunetic® 25mg Capsules (Sunitinib) – Targeted Therapy (Rx)

Quick answer: Sunetic 25mg (sunitinib) is a capsule that oncologists use to fine-tune treatment for kidney cancer, GIST and pancreatic neuroendocrine tumours. It suits patients who need a lower dose or a dose built from more than one strength. MedHub supplies it on prescription and delivers it across Pakistan.

For patients and families

What is Sunetic 25mg?

Each Sunetic 25mg capsule holds 25mg of sunitinib, a targeted cancer medicine from Pharmasol, which makes and markets it in Pakistan. Sunitinib works on the signals that help tumours grow and form new blood vessels. With fewer vessels feeding it, the tumour can stop growing or shrink.

What is it used for?

The medicine inside Sunetic 25mg is approved for:

• Pancreatic neuroendocrine tumours (pNET): growing tumours that surgery cannot remove. The daily dose here is often made up with a 25mg capsule plus a 12.5mg capsule.
• Kidney cancer (renal cell carcinoma): advanced or spread disease.
• Gastrointestinal stromal tumour (GIST): when imatinib no longer controls it or caused too many side effects.

Many people also move to this strength when their oncologist steps the dose down to ease side effects.

How is it taken?

Swallow the capsules whole once a day, and keep to a regular time. Food does not affect sunitinib, so you can take it after breakfast or on an empty stomach. Some patients take it every day without a break, while others follow a four-weeks-on, two-weeks-off pattern. Your doctor decides the dose and pattern for you, and your pharmacist explains how to combine capsules if you have more than one strength.

Common side effects

• Painful redness on the hands and feet
• Rising blood pressure, often found at clinic checks
• Loose stools, mouth ulcers and a change in taste
• Fatigue and low energy
• An underactive thyroid, picked up on blood tests

Report straight away any bleeding that will not stop, black or tarry stools, yellowing of the eyes, swollen legs with breathlessness, or sweating and shakiness from low blood sugar.

Storage

Keep Sunetic below 30°C in its original packaging, in a dry cupboard, and away from children.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We deliver the pack to your home or hospital in any city.

Relatives working in the UAE, UK and Saudi Arabia regularly arrange Sunetic 25mg for a mother or father in Pakistan through MedHub. If your plan combines strengths, we also hold Sunetic 12.5mg and the full-dose Sunetic 50mg (sunitinib). For GIST, see Glynib 400mg (imatinib) and the rest of our oncology catalogue.

For healthcare professionals

• Composition: sunitinib malate equivalent to 25 mg sunitinib per hard capsule
• Drug class: oral multikinase inhibitor (VEGFR, PDGFR, KIT)
• Indications: advanced or metastatic renal cell carcinoma; GIST after disease progression on, or intolerance to, imatinib; progressive, well-differentiated, unresectable or metastatic pancreatic neuroendocrine tumours
• Mechanism: blocks multiple receptor tyrosine kinases, including VEGFR-1 to -3, PDGFR-α and -β, KIT, FLT3, RET and CSF-1R, with anti-angiogenic and antitumour effects
• Label dose: RCC and GIST: 50 mg once daily on a 4 weeks on, 2 weeks off schedule; pNET: 37.5 mg once daily without a planned break. Modify by 12.5 mg increments based on safety and tolerability (pNET maximum 50 mg daily)
• Monitoring / key precautions: hepatotoxicity, sometimes fatal: liver function tests before treatment and with each cycle; monitor blood pressure, CBC, thyroid function, glucose, urine protein and electrolytes; caution in cardiac disease with LVEF monitoring; risk of QT prolongation, haemorrhage, impaired wound healing and osteonecrosis of the jaw; adjust dose with strong CYP3A4 inhibitors or inducers; embryo-fetal toxicity
• Storage: below 30°C; protect from moisture
• Manufactured and marketed in Pakistan by: Pharmasol (Pvt) Ltd
• Pack: 30 capsules

Frequently asked questions

What does Sunetic 25mg treat?

Sunetic 25mg treats advanced kidney cancer, GIST after imatinib, and pancreatic neuroendocrine tumours. Doctors also use it when a patient needs a reduced dose of sunitinib.

What is the Sunetic 25mg price in Pakistan?

Sunetic 25mg costs Rs 32,000 to Rs 49,000 per pack of 30 capsules. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Can you deliver Sunetic 25mg to Lahore, Karachi or Peshawar?

Yes. We deliver nationwide, covering Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad as well as smaller cities.

Is Sunetic 25mg sold without a prescription?

No. Sunitinib is prescription-only. Send your oncologist’s prescription to us on WhatsApp, and our pharmacist confirms it before we process the order.

What is the best way to take Sunetic 25mg?

Take it once daily at the same time, with or without food, and swallow it whole. Follow the cycle your oncologist sets, whether continuous or with planned breaks.

Why would my oncologist switch me from 50mg to Sunetic 25mg?

The usual reason is side effects, such as sore hands and feet, diarrhoea or high blood pressure. Lowering the dose often lets you stay on treatment longer while keeping the cancer under control.

Can Sunetic 25mg be combined with the 12.5mg capsule?

Yes. Taking one 25mg and one 12.5mg capsule together gives 37.5mg, the standard daily dose for pancreatic neuroendocrine tumours. Only combine strengths as your doctor prescribes.

Can I arrange Sunetic 25mg from the UAE, UK or Saudi Arabia?

Yes. Send the prescription on WhatsApp, and our team takes payment and delivers to your family member’s home or hospital anywhere in Pakistan.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.