Sonib® 200mg Tablets (Sorafenib) – Targeted Therapy (Rx)

Quick answer: Sonib 200mg (sorafenib) is a targeted cancer tablet for advanced liver cancer, advanced kidney cancer and certain thyroid cancers. You take it by mouth at home, as your oncologist directs. MedHub supplies it on prescription and delivers across Pakistan.

For patients and families

What is Sonib 200mg?

Sonib 200mg is a 200 mg sorafenib tablet made in Pakistan by Pharmasol. Sorafenib is a kinase inhibitor. It switches off several signals that tumour cells use to grow, and it also blocks the new blood vessels that feed a tumour. It is a targeted tablet, not a traditional drip chemotherapy.

What is it used for?

Doctors prescribe sorafenib for three cancers:

• Hepatocellular carcinoma: primary liver cancer that surgery cannot remove.
• Advanced renal cell carcinoma: kidney cancer, usually after other treatment has not worked well enough.
• Thyroid cancer: differentiated thyroid cancer that no longer responds to radioactive iodine.

For kidney cancer, doctors also use Sunetic 50mg (sunitinib), so ask your oncologist how the two compare for you. You can browse more in our oncology category.

How is it taken?

You swallow the tablets with a glass of water, either an hour before or two hours after food, because a heavy fatty meal can lower how much medicine your body absorbs. Your doctor decides the dose and may pause or lower it if side effects get hard to manage. Never change it yourself.

Common side effects

• Sore, red or peeling skin on the palms and soles (hand-foot skin reaction)
• Diarrhoea and loss of appetite
• Rash, dry skin and hair thinning
• Tiredness and weight loss
• High blood pressure, which your clinic checks regularly

Contact your oncologist straight away if you have chest pain, severe headache, bleeding or black stools, severe stomach pain, yellow eyes, or blistering skin.

Storage

Store the blister strips in the original pack below 30°C, in a dry spot away from steam, and keep them out of children’s reach. They do not need a fridge.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We deliver the pack to your home or hospital.

If you work in the UAE, UK or Saudi Arabia and want to support a parent with liver or kidney cancer, you can order from abroad. We handle the prescription check and delivery, and we remind you when the next pack is due.

For healthcare professionals

• Composition: sorafenib (as tosylate) 200 mg per film-coated tablet
• Drug class: multikinase inhibitor (RAF, VEGFR, PDGFR, KIT, RET)
• Indications: unresectable hepatocellular carcinoma; advanced renal cell carcinoma after failure of, or intolerance to, prior therapy; progressive, locally advanced or metastatic differentiated thyroid carcinoma refractory to radioactive iodine
• Mechanism: inhibits tumour cell proliferation through the RAF/MEK/ERK pathway and reduces angiogenesis by blocking VEGFR-2, VEGFR-3 and PDGFR-β
• Label dose: 400 mg (2 × 200 mg) twice daily, without food or with a low or moderate fat meal; continue until clinical benefit is lost or toxicity is unacceptable; interrupt or reduce for dermatologic toxicity or hypertension
• Monitoring / key precautions: monitor blood pressure weekly for the first 6 weeks; check for hand-foot skin reaction, bleeding, cardiac ischaemia, GI perforation and QT prolongation; monitor liver function, electrolytes, thyroid function and INR in patients on warfarin; hold before major surgery; avoid in pregnancy
• Storage: below 30°C, protect from moisture
• Manufactured and marketed in Pakistan by: Pharmasol (Pvt) Ltd
• Pack: 60 tablets

Frequently asked questions

What is Sonib 200mg used for?

Sonib 200mg treats advanced liver cancer, advanced kidney cancer and radioiodine-resistant thyroid cancer.

What is the Sonib 200mg price in Pakistan?

Sonib 200mg costs Rs 19,000 to Rs 36,000 per pack of 60 tablets. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Is Sonib 200mg available in Lahore, Karachi or Peshawar?

Yes. We deliver to Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad, and to other cities on request.

Do I need a prescription for Sonib 200mg?

Yes. It is a prescription-only cancer medicine. Send a clear photo of the prescription on WhatsApp, and our pharmacist checks it before confirming the order.

How is Sonib 200mg taken?

Swallow the tablets whole with water, on an empty stomach or with a light meal, at the times your oncologist gives you. Do not crush them.

How should Sonib 200mg be stored?

Keep it below 30°C in the original blister pack, away from moisture and out of children’s reach. It does not need a fridge.

How can I care for my hands and feet on Sonib 200mg?

Use a rich moisturizer, wear soft, well-fitting shoes and cotton socks, and avoid hot water and heavy rubbing. Tell your oncologist early, because a lower dose or short break often helps the skin recover.

Can I order Sonib 200mg for my father in Pakistan from abroad?

Yes. Many families in the UAE, UK and Saudi Arabia order through MedHub. Share the prescription on WhatsApp, and we arrange payment and delivery to his home.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.