Ifosfamin® 2g Injection (Ifosfamide) – Chemotherapy (Rx)

Quick answer: Ifosfamin 2g (ifosfamide) is an alkylating chemotherapy used for sarcomas, testicular cancer, lymphomas and some other solid tumours. It is given as a drip into a vein in hospital, always with a bladder-protecting medicine called mesna. MedHub supplies it on prescription and delivers across Pakistan.

For patients and families

What is Ifosfamin 2g?

Ifosfamin 2g is a vial containing 2 grams of ifosfamide, made in Pakistan by Pharmedic Laboratories. The hospital pharmacy dissolves and dilutes it before use. Ifosfamide belongs to the alkylating agents. The liver turns it into active substances that link the two strands of DNA together, so cancer cells can no longer copy their genes and divide.

What is it used for?

Specialists use ifosfamide, nearly always combined with other chemotherapy, for:

• Soft tissue sarcomas in adults and children
• Bone cancers such as osteosarcoma and Ewing sarcoma
• Testicular germ cell tumours, particularly when the cancer has come back
• Hodgkin and non-Hodgkin lymphoma, often as salvage treatment
• Some lung, ovarian, cervical and breast cancers

Sarcoma regimens commonly combine it with Naprodox 50mg (doxorubicin), while testicular cancer plans may add Cispatin 50mg (cisplatin).

How is it given?

Ifosfamide runs into a vein over several hours, often on a few days in a row, and some patients stay in hospital for each cycle. Mesna goes in alongside it to protect the bladder lining, and the team gives extra fluids so you pass urine often. Your doctor decides the dose and schedule, and checks your kidneys, blood counts and urine before each cycle.

Common side effects

• Nausea and vomiting, controlled with anti-sickness medicines
• Hair loss
• Low blood counts and a higher risk of infection
• Blood in the urine or burning when passing urine
• Drowsiness or feeling muddled during the infusion

Tell the nurse or doctor immediately about confusion, hallucinations, extreme sleepiness, fits, red urine, reduced urine output or a fever after you go home.

Storage

Store the unopened vial below 25°C in its carton. It does not need a fridge. Hospitals prepare the infusion just before use, so most families never handle the medicine directly.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We pack the vials and deliver them to your hospital or home.

Families in the UAE, UK and Saudi Arabia often source Ifosfamin 2g for a parent or child having treatment in Pakistan through us. Browse the rest of our oncology medicines for other drugs in the same regimen.

For healthcare professionals

• Composition: ifosfamide 2 g per vial, powder for solution for injection or infusion
• Drug class: oxazaphosphorine alkylating agent (nitrogen mustard analogue)
• Indications: germ cell testicular cancer (including third-line use in combination); soft tissue sarcomas; osteosarcoma and Ewing sarcoma; Hodgkin and non-Hodgkin lymphoma; small cell and non-small cell lung cancer; ovarian, cervical and breast cancer, in combination regimens
• Mechanism: prodrug activated by hepatic CYP450 to ifosforamide mustard, which forms DNA cross-links; the metabolite acrolein causes urothelial toxicity and chloroacetaldehyde contributes to neurotoxicity and nephrotoxicity
• Label dose: 1.2 g/m²/day IV for 5 consecutive days every 3 weeks (testicular cancer); fractionated regimens of 8–12 g/m² per cycle over 3–5 days, or 5–6 g/m² (maximum 10 g) as a 24-hour infusion, repeated every 2–4 weeks; give with mesna and at least 2 litres of fluid per day
• Monitoring / key precautions: urinalysis for haematuria before each dose; renal function and electrolytes (risk of Fanconi syndrome and nephrotoxicity); full blood count; watch for encephalopathy, especially with low albumin or renal impairment; cardiotoxicity at high doses; contraindicated in urinary outflow obstruction and pregnancy
• Storage: below 25°C
• Manufactured and marketed in Pakistan by: Pharmedic Laboratories (Pvt) Ltd
• Pack: 1 vial

Frequently asked questions

What is Ifosfamin 2g used for?

Ifosfamin 2g is used for soft tissue and bone sarcomas, testicular cancer and lymphomas, plus some lung, ovarian, cervical and breast cancers, as part of combination chemotherapy.

What is the Ifosfamin 2g price in Pakistan?

Ifosfamin 2g costs Rs 3,095 per vial. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Can I get Ifosfamin 2g in Lahore, Karachi or Peshawar?

Yes. MedHub delivers across Pakistan, including Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad.

Do I need a prescription for Ifosfamin 2g?

Yes. Ifosfamide is a prescription-only chemotherapy. Send the prescription on WhatsApp, and our pharmacist confirms the details before your order goes out.

How is Ifosfamin 2g given?

A nurse gives it as a slow drip into a vein over several hours, usually on consecutive days, with mesna and extra fluids. Many patients stay in hospital during each cycle.

Why is mesna given with Ifosfamin 2g?

Mesna protects the bladder. When the body breaks down ifosfamide, it makes a substance that irritates the bladder lining and can cause bleeding. Mesna neutralizes it, so ask your doctor to include it on the prescription.

Can Ifosfamin 2g cause confusion?

Yes, in some patients. Ifosfamide can affect the brain, causing sleepiness, confusion or hallucinations during or soon after the drip. It usually settles after stopping, but the team needs to know right away.

Can I arrange Ifosfamin 2g for family in Pakistan from abroad?

Yes. Families in the UAE, UK and Saudi Arabia order through MedHub. Send the prescription on WhatsApp, and we arrange payment and delivery to the hospital.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.