Zoladex® 3.6mg Implant (Goserelin) – Hormone Therapy (Rx)

Quick answer: Zoladex 3.6mg (goserelin) is a hormone implant for prostate cancer, breast cancer in women before the menopause, and some gynaecological conditions such as endometriosis. A doctor or nurse injects it under the skin of the tummy every 28 days. MedHub supplies it on prescription with delivery across Pakistan.

For patients and families

What is Zoladex 3.6mg?

Zoladex 3.6mg is a tiny rod of goserelin, about the size of a grain of rice, preloaded in a single-use syringe. Once under the skin, it releases the medicine slowly over four weeks. Goserelin tells the pituitary gland in the brain to stop signalling the testicles or ovaries. As a result, testosterone in men and oestrogen in women fall to very low levels, which slows cancers that feed on these hormones.

What is it used for?

• Prostate cancer that responds to hormone treatment, including advanced disease and, with radiotherapy, high-risk cancer that has not spread.
• Breast cancer in women before or around the menopause, when the cancer is hormone-sensitive, in early or advanced stages.
• Endometriosis, to ease pain and shrink patches of tissue outside the womb.
• Uterine fibroids before surgery, and thinning the womb lining before certain procedures.
• Fertility treatment, to control the natural cycle during assisted conception.

Men with prostate cancer often take Casodex 50mg (bicalutamide) during the first weeks of treatment, and some women with breast cancer use Arimidex 1mg (anastrozole) alongside it.

How is it given?

A doctor or nurse injects the implant under the skin of the lower abdomen, usually every 28 days, at a clinic or hospital. A numbing cream or injection can make it more comfortable. The implant dissolves on its own, so nothing needs removing. Your doctor decides how long you continue. Try not to miss an appointment, because hormone levels can rise again.

Common side effects

• Hot flushes and sweating
• Lower sex drive, and erection problems in men
• Vaginal dryness and breast changes in women
• Mood changes, tiredness and joint aches
• Bruising or soreness where the implant went in

Tell your doctor at once about severe pain, swelling or bleeding at the injection site, new back pain, leg weakness or trouble passing urine in the first weeks, or chest pain. Long-term use can thin the bones, so ask about calcium, vitamin D and bone checks.

Storage

Keep the sealed pouch below 25°C and away from direct heat. It does not need a fridge. Bring it to your clinic unopened.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We deliver the implant to your home or clinic before your next appointment.

Families in the UAE, UK and Saudi Arabia often order Zoladex 3.6mg every month for a parent in Pakistan, timed to each 28-day visit. You can browse our full range of oncology medicines.

For healthcare professionals

• Composition: goserelin (as acetate) 3.6 mg implant in a prefilled single-dose applicator
• Drug class: luteinizing hormone-releasing hormone (LHRH) agonist
• Indications: prostate cancer suitable for hormonal manipulation, including neoadjuvant and adjuvant use with radiotherapy in high-risk localized or locally advanced disease; advanced and early oestrogen receptor-positive breast cancer in pre- and perimenopausal women; endometriosis; endometrial thinning before ablation; uterine fibroids with iron before surgery; pituitary downregulation in assisted reproduction
• Mechanism: continuous LHRH receptor stimulation desensitizes the pituitary, suppressing LH and FSH and reducing testosterone to castrate levels and oestradiol to postmenopausal levels
• Label dose: one 3.6 mg implant subcutaneously into the anterior abdominal wall every 28 days
• Monitoring / key precautions: initial testosterone flare in men, so consider an antiandrogen and watch closely for spinal cord compression or ureteric obstruction; injection-site vascular injury, with care in low BMI or anticoagulated patients; loss of bone mineral density; hyperglycaemia and diabetes; QT prolongation with androgen deprivation; mood changes and depression; exclude pregnancy and use non-hormonal contraception
• Storage: below 25°C
• Manufacturer: AstraZeneca UK Ltd, United Kingdom
• Marketed in Pakistan by: LCI
• Pack: 1 implant (prefilled syringe)

Frequently asked questions

What is Zoladex 3.6mg used for?

It treats hormone-sensitive prostate and breast cancer, and gynaecological conditions such as endometriosis and fibroids. It works by lowering testosterone or oestrogen.

What is the Zoladex 3.6mg price in Pakistan?

Zoladex 3.6mg costs Rs 21,500 to Rs 28,500 per implant. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Is Zoladex 3.6mg available in Lahore, Karachi or Peshawar?

Yes. MedHub delivers across Pakistan, including Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad.

Do I need a prescription for Zoladex 3.6mg?

Yes. Goserelin is a prescription-only hormone treatment. Send a photo of your specialist’s prescription on WhatsApp, and our pharmacist checks it before confirming.

How is Zoladex 3.6mg given?

A doctor or nurse injects the small implant under the skin of your tummy, normally once every 28 days. It dissolves slowly and releases the medicine over the month.

Does Zoladex 3.6mg need to be kept in the fridge?

No. Store it below 25°C in its sealed pouch, out of direct sunlight and heat.

Can I get pregnant while using Zoladex 3.6mg?

Goserelin must not be used in pregnancy. Although periods usually stop, it is not a reliable contraceptive, so use a non-hormonal method such as condoms or a copper coil throughout treatment.

Can I order Zoladex 3.6mg for my parents in Pakistan from abroad?

Yes. Families in the UAE, UK and Saudi Arabia regularly order through MedHub. Share the prescription and the next injection date on WhatsApp, and we deliver in good time.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.