Mylonib® 15mg Tablets (Ruxolitinib) – Targeted Therapy (Rx)

Quick answer: Mylonib 15mg (ruxolitinib) is a Pakistani-made JAK inhibitor tablet used for myelofibrosis, polycythaemia vera and graft-versus-host disease. Patients take it by mouth at home. MedHub supplies it on a valid prescription and sends it to your home or hospital anywhere in Pakistan.

For patients and families

What is Mylonib 15mg?

Mylonib 15mg is a tablet of ruxolitinib produced in Pakistan by Pharmasol. Ruxolitinib calms an overactive signalling pathway, called JAK-STAT, inside the cells that make blood. When that pathway runs unchecked, the bone marrow scars, the spleen swells and people lose weight, sweat at night and feel worn out. By quietening it, the medicine often eases the swelling under the left ribs and lifts energy levels.

What is it used for?

• Graft-versus-host disease: for patients aged 12 and over whose acute or chronic GvHD has not settled with steroids after a stem cell transplant.
• Polycythaemia vera: a condition with too many red cells, once hydroxyurea has failed or caused side effects.
• Myelofibrosis: primary myelofibrosis, or scarring that develops after polycythaemia vera or essential thrombocythaemia, to reduce spleen size and related symptoms.

If your specialist lowers your dose later, the Mylonib 5mg tablet may suit you. We also keep Jakavi 15mg, and you can see our full range of hematology medicines.

How is it taken?

This is an oral tablet, so you take it at home rather than in a hospital. Patients usually swallow it with a glass of water morning and evening, and food makes no difference. Your doctor decides the dose, and blood counts guide every change. Your doctor or pharmacist explains what to do if you forget a tablet. Never stop Mylonib 15mg without medical advice, as symptoms may return within days.

Common side effects

• Bruising or nosebleeds from a low platelet count
• Tiredness from a fall in haemoglobin
• Feeling dizzy or getting headaches
• Raised cholesterol and some weight gain
• Bladder infections or a shingles rash

Seek medical help at once for a high temperature, bleeding that will not stop, a blistering rash on one side of the body, or sudden changes in thinking, speech or vision.

Storage

Store the strips in their carton below 30°C and keep them dry. Keep them out of sight and reach of children, and avoid hot cars or sunny window sills.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We deliver the pack to your home or clinic, wherever you live.

Families in the UAE, UK and Saudi Arabia often set up regular monthly orders for a parent who takes this tablet long term. Share the prescription once, and our team reminds you before the next pack is due.

For healthcare professionals

• Composition: ruxolitinib (as phosphate) 15 mg per tablet
• Drug class: Janus kinase inhibitor (JAK1/JAK2)
• Indications: splenomegaly or symptoms in adults with primary, post-polycythaemia vera or post-essential thrombocythaemia myelofibrosis; adults with polycythaemia vera resistant to or intolerant of hydroxyurea; acute or chronic graft-versus-host disease in patients 12 years and older with inadequate response to corticosteroids or other systemic therapies
• Mechanism: competitive inhibition of JAK1 and JAK2 kinase activity, lowering STAT phosphorylation and pro-inflammatory cytokine levels
• Label dose: myelofibrosis starting dose 15 mg twice daily for platelets 100,000–200,000/mm³ or 20 mg twice daily for platelets above 200,000/mm³; polycythaemia vera and GvHD 10 mg twice daily; adjust to response and blood counts
• Monitoring / key precautions: blood counts every 2–4 weeks until stable, then as indicated; exclude active tuberculosis and check hepatitis B status; monitor for infections, herpes zoster, PML and skin cancers; check lipids; lower the dose with strong CYP3A4 inhibitors and in renal or hepatic impairment; avoid abrupt withdrawal
• Storage: below 30°C; protect from moisture
• Manufactured and marketed in Pakistan by: Pharmasol (Pvt) Ltd
• Pack: 60 tablets

Frequently asked questions

What does Mylonib 15mg treat?

It treats myelofibrosis, polycythaemia vera that has not responded to hydroxyurea, and steroid-resistant graft-versus-host disease after a transplant.

What is the Mylonib 15mg price in Pakistan?

Mylonib 15mg costs Rs 201,780 per pack of 60 tablets. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Can you deliver Mylonib 15mg to Lahore, Karachi or Peshawar?

Yes. We deliver nationwide, including Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad.

Is a prescription needed for Mylonib 15mg?

Yes. You need a prescription from a haematologist or oncologist. Send us a clear photo of it on WhatsApp, and our pharmacist reviews it before dispatch.

When should I take Mylonib 15mg each day?

Most people take it twice daily, roughly 12 hours apart, with or without a meal. Keep to the timing on your prescription and attend each blood test.

Is Mylonib 15mg the same medicine as Jakavi?

Both contain ruxolitinib at the same strength. Mylonib is made locally by Pharmasol, and Jakavi is the original Swiss brand. Your specialist decides which brand to prescribe, and you should not switch without asking them.

How long does one pack of Mylonib 15mg last?

At one tablet twice a day, a pack of 60 tablets lasts about 30 days. Order a few days before you run out so treatment does not break.

Can relatives abroad buy Mylonib 15mg for a parent in Pakistan?

Yes. Many customers in the UAE, UK and Saudi Arabia pay from abroad while we deliver to their parents’ home or hospital. Send the prescription on WhatsApp to begin.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.