Decibine® 50mg Injection (Decitabine) – Chemotherapy (Rx)

Quick answer: Decibine 50mg (decitabine) is a chemotherapy medicine for myelodysplastic syndromes and for acute myeloid leukaemia in adults who cannot have intensive treatment. A nurse gives it as a drip into a vein over several days. MedHub supplies it on prescription and delivers across Pakistan.

For patients and families

What is Decibine 50mg?

Decibine 50mg is a vial of decitabine powder made in Pakistan by AJM Pharma. Decitabine belongs to the hypomethylating agents. It helps damaged bone marrow cells mature more normally and stops the faulty ones from multiplying. Doctors often choose it when a patient is older or too unwell for strong, intensive chemotherapy.

What is it used for?

Blood specialists use decitabine for:

• Myelodysplastic syndromes (MDS): a group of bone marrow disorders in which the marrow makes too few healthy blood cells.
• Acute myeloid leukaemia (AML): in adults aged 65 and over who cannot have standard induction chemotherapy.

Some patients with MDS take other medicines too, for example Lenaido 10mg (lenalidomide), but your haematologist picks the plan that fits your blood tests. See all our haematology medicines as well.

How is it given?

The pharmacy mixes the powder into a solution, and a nurse gives it as a drip over about an hour, in a hospital or day-care ward. Treatment usually comes in cycles that last several weeks, with a rest period between them. Your doctor decides the schedule and the dose, and adjusts them according to your blood counts.

Common side effects

• Low white cells, red cells or platelets, which can mean infections, tiredness or bruising
• Fever and chills
• Nausea, constipation or diarrhoea
• Cough, headache and joint aches
• Swollen ankles

Phone your care team straight away if you have a temperature of 38°C or more, unusual bleeding, black stools, breathlessness or a sore mouth that stops you eating.

Storage

Store the unopened vial in its carton below 25°C, in a dry place away from direct sun. It does not need a fridge. Once the pharmacy has mixed it, the solution must be used quickly, so hospital staff handle that step.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We pack the vial with care and deliver it to your door or hospital.

If you live in the UAE, UK or Saudi Arabia and a parent is being treated in Pakistan, you can send us the prescription from there and pay remotely. Another option in our range is Idarubicin AHP 10mg, which doctors use in more intensive leukaemia treatment.

For healthcare professionals

• Composition: decitabine 50 mg per vial, lyophilized powder for concentrate for solution for infusion
• Drug class: hypomethylating agent, nucleoside metabolic inhibitor
• Indications: myelodysplastic syndromes, including previously treated and untreated, de novo and secondary MDS; acute myeloid leukaemia in adults aged 65 years and over who are not candidates for standard induction chemotherapy
• Mechanism: incorporates into DNA and traps DNA methyltransferase, causing hypomethylation and cell differentiation or death
• Label dose: AML 20 mg/m² by IV infusion over 1 hour once daily for 5 consecutive days, repeated every 4 weeks; MDS regimens include 15 mg/m² every 8 hours for 3 days every 6 weeks, or 20 mg/m² daily for 5 days every 4 weeks; delay or reduce the dose for haematological toxicity
• Monitoring / key precautions: full blood count before each cycle; monitor for myelosuppression, infection and bleeding; check liver and renal function; use effective contraception during and after treatment; contraindicated in pregnancy and breastfeeding
• Storage: below 25°C; reconstituted solution must be diluted with cold infusion fluid and used within the label time limits
• Manufactured and marketed in Pakistan by: AJM Pharma (Pvt) Ltd
• Pack: 1 vial

Frequently asked questions

What is Decibine 50mg used for?

Decibine 50mg treats myelodysplastic syndromes and acute myeloid leukaemia in adults aged 65 and over who cannot have intensive chemotherapy.

What is the Decibine 50mg price in Pakistan?

Decibine 50mg costs Rs 29,000 to Rs 36,000 per vial. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Is Decibine 50mg available in Lahore, Karachi or Peshawar?

Yes. We deliver to Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad, as well as other cities on request.

Do I need a prescription for Decibine 50mg?

Yes. It is a prescription-only chemotherapy medicine. Send a clear photo of the prescription on WhatsApp, and our pharmacist checks it before we confirm the order.

How is Decibine 50mg given?

A nurse gives it as a one-hour drip into a vein, usually on several days in a row at the start of each cycle. You do not take it at home.

How should Decibine 50mg be stored?

Keep the sealed vial in its carton below 25°C, dry and out of direct sunlight. It does not need refrigeration.

Does Decibine 50mg cause hair loss?

Hair thinning can happen, but it is less common than with many other chemotherapy medicines. Low blood counts, fever and infection need more attention, so keep your blood test appointments.

Can I order Decibine 50mg for my mother in Pakistan from abroad?

Yes. Many families in the UAE, UK and Saudi Arabia order through MedHub. Send the prescription on WhatsApp, and we arrange payment and delivery to her home or hospital.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.