Mylonib® 5mg Tablets (Ruxolitinib) – Targeted Therapy (Rx)

Quick answer: Mylonib 5mg (ruxolitinib) is the lowest-strength tablet of a JAK inhibitor for myelofibrosis, polycythaemia vera and graft-versus-host disease. Doctors often use it for smaller or adjusted doses. MedHub supplies it on prescription, and we deliver it to any town or city in Pakistan.

For patients and families

What is Mylonib 5mg?

Mylonib 5mg contains 5 milligrams of ruxolitinib and comes from Pharmasol, a Pakistani manufacturer. Ruxolitinib blocks two enzymes, JAK1 and JAK2, that drive certain blood disorders and some immune reactions after a transplant. The small strength gives your specialist fine control, because the right amount often changes as your blood counts rise or fall.

What is it used for?

Specialists prescribe ruxolitinib in three situations:

• Polycythaemia vera that hydroxyurea has not kept under control, or that patients cannot tolerate hydroxyurea for.
• Myelofibrosis, to reduce a swollen spleen, night sweats, itching and tiredness.
• Graft-versus-host disease in people aged 12 or older after a donor stem cell transplant, when steroids have not worked well enough.

People whose platelets are on the low side, or who have kidney or liver problems, often start on smaller doses built from this tablet.

How is it taken?

You swallow the tablets whole with water, generally in the morning and at night, and you can take them with or without food. Some people take more than one 5mg tablet at a time to make up their prescribed amount. Your doctor decides the dose and checks your blood regularly before changing it. Do not stop treatment abruptly unless your doctor tells you to.

Common side effects

• Anaemia, causing tiredness or shortness of breath
• Bruising easily because of low platelets
• Shingles or urine infections
• Higher cholesterol, weight gain and dizziness

Speak to your care team urgently about fever or chills, bleeding gums, blood in urine or stools, or any new muddled thinking or blurred vision.

Storage

Store the tablets below 30°C in their original pack to shield them from damp. Keep them away from children and do not move them into a pill box until close to the time you need them.

How to order from MedHub

1. Send a photo of your prescription on WhatsApp.
2. Our pharmacist confirms the price and stock with you.
3. We send the tablets to your address or treating hospital.

Families in the UAE, UK and Saudi Arabia frequently buy Mylonib 5mg for parents back home and ask us to deliver straight to the house. If your doctor moves you to a higher dose, look at Mylonib 15mg or the original brand Jakavi 15mg. You can also browse our hematology medicines.

For healthcare professionals

• Composition: ruxolitinib (as phosphate) 5 mg per tablet
• Drug class: JAK1 and JAK2 kinase inhibitor
• Indications: adults with primary myelofibrosis, post-polycythaemia vera myelofibrosis or post-essential thrombocythaemia myelofibrosis with splenomegaly or symptoms; adults with polycythaemia vera resistant to or intolerant of hydroxyurea; patients aged 12 years and older with acute or chronic graft-versus-host disease and inadequate response to corticosteroids or other systemic therapies
• Mechanism: blocks JAK1/JAK2-mediated signalling of cytokines and growth factors involved in haematopoiesis and immune function
• Label dose: myelofibrosis 15–20 mg twice daily by baseline platelet count, with 5 mg twice daily used as a starting dose when platelets are 50,000–100,000/mm³; polycythaemia vera 10 mg twice daily; GvHD 10 mg twice daily; titrate in 5 mg steps
• Monitoring / key precautions: monitor blood counts every 2–4 weeks until stable; rule out active TB and test for hepatitis B; observe for serious infections, herpes zoster, PML and non-melanoma skin cancer; check lipids; reduce dose in renal or hepatic impairment and with strong CYP3A4 inhibitors; taper on discontinuation
• Storage: below 30°C; protect from moisture
• Manufactured and marketed in Pakistan by: Pharmasol (Pvt) Ltd
• Pack: 60 tablets

Frequently asked questions

What is Mylonib 5mg used for?

It is used for myelofibrosis, polycythaemia vera after hydroxyurea and graft-versus-host disease that steroids have not controlled. The 5mg tablet suits lower or adjusted doses.

What is the Mylonib 5mg price in Pakistan?

Mylonib 5mg costs Rs 72,000 per pack of 60 tablets. Prices can change with supply, so message us on WhatsApp for today’s price before you order.

Do you supply Mylonib 5mg in Lahore, Karachi or Peshawar?

Yes. MedHub delivers to all major cities, including Islamabad, Rawalpindi, Lahore, Karachi, Peshawar, Multan and Faisalabad.

Can I buy Mylonib 5mg without a prescription?

No. Ruxolitinib needs a specialist’s prescription and regular blood tests. WhatsApp us a photo of the prescription, and our pharmacist confirms it before processing your order.

How should Mylonib 5mg be taken?

Take it by mouth, normally twice a day, with or without food. Your prescription may ask you to take one or more tablets each time.

Why would my doctor prescribe Mylonib 5mg instead of 15mg?

Doctors choose the 5mg strength for patients with low platelets, kidney or liver problems, or interacting medicines. They also use it to make small dose changes without splitting tablets.

Can Mylonib 5mg tablets be combined to make a higher dose?

Yes, if your doctor prescribes it that way. For example, two 5mg tablets give 10mg. Always follow the exact number of tablets written on your prescription.

How can I order Mylonib 5mg for my parents from overseas?

Send the prescription on WhatsApp from the UAE, UK, Saudi Arabia or anywhere else. We confirm payment with you and deliver to your parents’ address in Pakistan.

Last updated: 3 October 2026

This information is for general awareness only and is not medical advice. Always consult your doctor before starting, stopping or changing any medicine.